There’s often an undercurrent of existential fatigue in games that look back at their legacy. Dark Souls III’s dying kingdom, Metal Gear Solid 4’s decrepit Snake. So when Capcom showed us an ageing Leon Kennedy entering the ruins of the police station that marked the start of his journey from rookie cop to hardened veteran, it felt tinged with ennui as much as nostalgia. That self-reflective swansong for this 30-year series may still happen one day, but Requiem isn’t it. Even at its dourest and most pensive, this is less a song for the dead, more a knees-up in honour of the rocket launchers and typewriters that came before. Leon may be getting on a bit, but this is Capcom as energised, devious and goofy as ever.
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从1994年 FGFR3靶点被证实与ACH相关，到2021年Vosoritide获批上市，ACH患者等待了近30年，才迎来首款针对性治疗药物。而随着Infigratinib叩响上市的大门，以及身后一众迭代疗法的逼近，ACH精准治疗的新大门正加速开启。这也是罕见病从被行业忽略到逐渐被重视的真实缩影。
In one young couple's diary given to them for the project, Sumaira describes her partner coming home, the dinner she has cooked, the hug in the hallway, the two of them eating together at the table.